Searchable abstracts of presentations at key conferences in endocrinology

ea0028p149 | Neoplasia, cancer and late effects | SFEBES2012

Use of Vandetenib in metastatic medullary carcinoma of thyroid in a paediatric patient with Multiple Endocrine Neoplasia (MEN)2B

Narayanan Vidya , Bradshaw Nicola , Davidson Rosemarie , Welbury Richard , Macgregor Fiona , Ronghe Milind , Reed Nick , Shaikh Mohammed

Vandetenib has been used as novel treatment of locally invasive medullary carcinoma of thyroid. We report the use of Vandetenib in a paediatric patient with inoperable medullary carcinoma of thyroid gland. Our patient presented to the dental surgeons at age 12 years with tongue and lip swellings. Biopsy demonstrated mucosal neuromas suggestive of MEN2B. He was clinically euthyroid but had a firm goitre. Ultrasound showed a large heterogenous thyroid mass encasing the common ca...